DWI Traveling Human Phantom Study

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DWI Traveling Human Phantom Study
DWI Traveling Human Phantom Study
  •   dataset_description.json
  •   README
  • code
  • sourcedata
  • sub-THP0001
  • sub-THP0002
  • sub-THP0003
  • sub-THP0004
  • sub-THP0005
  • sub-THPBALL


This Datasets is from a Traveling Human Phantom (THP) dataset that was collected for a multi-site neuroimaging reliability study. The THP dataset includes repeated multi-modal magnetic resonance (MR) images obtained for five healthy controls performed at eight imaging centers. The modalities include diffusion weighted images (DWI) and three-dimensional T1 weighted MP-RAGE and T2 SPACE sequences. Intra-subject and inter-site variability for MRI scans was and can be assessed as repeated images were taken across multiple imaging protocols.

Another use for the THP dataset could be to evaluate and improve one's tool against multi-modal and multi-site data. In addition to the THP dataset, which is useful as it is, we share our processed results. DWI datasets were processed to produce common rotationally invariant scalar images and diffusion tensor images. Anatomical images, T1 and T2, were processed with the BRAINSTools suite to produce anatomical segmentations.

@article{magnotta2012multicenter, abstract = {A number of studies are now collecting diffusion tensor imaging (DTI) data across sites. While the reliability of anatomical images has been established by a number of groups, the reliability of DTI data has not been studied as extensively. In this study, five healthy controls were recruited and imaged at eight imaging centers. Repeated measures were obtained across two imaging protocols allowing intra-subject and inter-site variability to be assessed. Regional measures within white matter were obtained for standard rotationally invariant measures: fractional anisotropy, mean diffusivity, radial diffusivity, and axial diffusivity. Intra-subject coefficient of variation (CV) was typically {\textless}1{%} for all scalars and regions. Inter-site CV increased to {~{}}1{%}-3{%}. Inter-vendor variation was similar to inter-site variability. This variability includes differences in the actual implementation of the sequence.}, author = {Magnotta, Vincent a. and Matsui, Joy T. and Liu, Dawei and Johnson, Hans J. and Long, Jeffrey D. and Bolster, Bradley D. and Mueller, Bryon a. and Lim, Kelvin O. and Mori, Susumu and Helmer, Karl and Turner, Jessica a. and Lowe, Mark J. and Aylward, Elizabeth and Flashman, Laura a. and Bonett, Greg and Paulsen, Jane S.}, doi = {10.1089/brain.2012.0112}, isbn = {8605457767}, issn = {2158-0014}, journal = {Brain Connectivity}, keywords = {diffusion tensor,fractional anisotropy,magnetic resonance,mean diffusivity,reliability,white matter}, mendeley-groups = {ReginaThesis,BiosketchReferences,JoysThesis,JoyCrossSectionalDWI,TEMP{_}HOWES{_}RE}, month = {jan}, number = {6}, pages = {121018043201009}, pmid = {23075313}, publisher = {Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA}, title = {{Multi-Center Reliability of Diffusion Tensor Imaging}}, url = {}, volume = {2}, year = {2012} }


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